Name: Cardiac Actions of Protein Kinase C Isoforms
Creator: Susan F, Steinberg
Keywords: Isoenzymes, 0301 basic medicine, 0303 health sciences, 03 medical and health sciences, Myocardium, Animals, Humans, Phosphorylation, Protein Kinase C, 3. Good health

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 2012 English Publisher:American Physiological SocietyJournal:Physiology, volume 27, pages 130-139 (issn: 1548-9213, eissn: 1548-9221,

Authors: Susan F, Steinberg;

doi: 10.1152/physiol.00009.2012

pmid: 22689788

pmc: PMC3582339

Cardiac Actions of Protein Kinase C Isoforms

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Abstract

Protein kinase C (PKC) isoforms have emerged as important regulators of cardiac contraction, hypertrophy, and signaling pathways that influence ischemic/reperfusion injury. This review focuses on newer concepts regarding PKC isoform-specific activation mechanisms and actions that have implications for the development of PKC-targeted therapeutics.

Related Organizations

Columbia University
United States
King’s University
United States

Keywords

Isoenzymes, Myocardium, Animals, Humans, Phosphorylation, Protein Kinase C

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