Recent Advances in Senolysis for Age-Related Diseases

Sae Aratani; Makoto Nakanishi

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Physiology

Article . 2023 . Peer-reviewed

Data sources: Crossref

Physiology

Article . 2023

Data sources: Europe PubMed Central

Recent Advances in Senolysis for Age-Related Diseases

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 2023 English Publisher:American Physiological SocietyJournal:Physiology, volume 38, pages 205-216 (issn: 1548-9213, eissn: 1548-9221,

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Authors: Sae Aratani; Makoto Nakanishi;

doi: 10.1152/physiol.00003.2023

pmid: 37191645

Recent Advances in Senolysis for Age-Related Diseases

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Abstract

Cellular senescence plays a central role in aging and geriatric diseases. Senolysis is a promising new strategy that selectively kills and eliminates senescent cells to control aging. To date, various senolytic drugs have been discovered and shown efficacy. This review highlights how we can benefit from senolysis.

Related Organizations

University of Tokyo
Japan
Nippon Medical School
Japan

Keywords

Aging, Humans, Cellular Senescence, Aged

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	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	11
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%