Renal Cell-to-Cell Communication via Extracellular ATP

descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 2005 English Publisher:American Physiological SocietyJournal:Physiology, volume 20, pages 86-90 (issn: 1548-9213, eissn: 1548-9221,

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Authors: Peter, Komlosi; Attila, Fintha; P Darwin, Bell;

doi: 10.1152/physiol.00002.2005

pmid: 15772296

Renal Cell-to-Cell Communication via Extracellular ATP

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Abstract

In the kidney, macula densa cells communicate with the mesangial cell-afferent arteriolar smooth muscle cell complex through ATP signaling. This signaling process involves release of ATP across the macula densa basolateral membrane through a maxi anion channel and the interaction of ATP with purinergic P2 receptors.

Related Organizations

University of Alabama at Birmingham
United States

Keywords

Adenosine Triphosphate, Animals, Humans, Cell Communication, Extracellular Space, Kidney

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