
pmid: 14500797
Proteins that belong to the ATP-binding cassette superfamily span from bacteria to humans and comprise one of the largest protein families. These proteins are characterized by the presence of two nucleotide-binding domains, and recent studies suggest that association and dissociation of these domains is a common basic molecular mechanism of operation that couples ATP binding/hydrolysis to substrate transport across membranes.
Adenosine Triphosphate, Binding Sites, Nucleotides, Molecular Sequence Data, Animals, Biological Transport, Active, Humans, ATP-Binding Cassette Transporters, Amino Acid Sequence
Adenosine Triphosphate, Binding Sites, Nucleotides, Molecular Sequence Data, Animals, Biological Transport, Active, Humans, ATP-Binding Cassette Transporters, Amino Acid Sequence
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