Nonredundant Gap Junction Functions

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 2003 English Publisher:American Physiological SocietyJournal:Physiology, volume 18, pages 95-99 (issn: 1548-9213, eissn: 1548-9221,

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Authors: Thomas W, White;

doi: 10.1152/nips.01430.2002

pmid: 12750443

Nonredundant Gap Junction Functions

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Abstract

The need for molecular heterogeneity of gap junction channel proteins in vivo has been enigmatic. Recently, functional replacement of one channel gene with another in mice and flies has revealed that cellular health depends not simply on gap junction communication but also requires the correct type of intercellular channel subunit.

Related Organizations

State University of New York at Potsdam
United States
State University of New York
United States

Keywords

Gap Junctions, Membrane Proteins, Nerve Tissue Proteins, Eye, Connexins, Connexin 43, Lens, Crystalline, Animals, Drosophila Proteins, Humans, Drosophila

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