Fusion Pore in Live Cells

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 2002 English Publisher:American Physiological SocietyJournal:Physiology, volume 17, pages 219-222 (issn: 1548-9213, eissn: 1548-9221,

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Authors: Bhanu P, Jena;

doi: 10.1152/nips.01394.2002

pmid: 12433973

Fusion Pore in Live Cells

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Abstract

Earlier electrophysiological measurements on live secretory cells suggested the presence of fusion pores at the plasma membrane, where secretory vesicles fuse to release vesicular contents. Recent studies using atomic force microscopy demonstrate for the first time the presence of the fusion pore and reveal its morphology and dynamics at near-nanometer resolution and in real time.

Related Organizations

Wayne State University
United States
Wayne State College
United States

Keywords

Secretory Vesicles, Cell Membrane, Membrane Fusion, Pancreas

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