Preliminary studies indicate that thermography is useful in evaluating patients with osteosarcoma. It may be employed to determine local extent and vascularity of the primary tumor, recurrence, and metastases. The thermogram may present findings not immediately detectable by conventional diagnostic methods. Procedure We utilize a high-speed infrared scanning device, the Pyroscan, which gives 40,000 separate temperature measurements in thirty seconds and records on newspaper facsimile paper. These scans measure a temperature range of 6° C with sensitivity of 0.3° C. The polarity is modified so that the warmer areas are recorded darker than the colder areas. The scans are performed in a room in which the temperature is 68° F, and the skin areas to be measured are exposed to this environment for eight minutes prior to thermography. Nineteen patients with osteosarcoma have been evaluated in two and a half years. The involved site was scanned in four positions; anteroposterior, postero-anterior, and both later...