Sarcoidosis of the skull is quite rare, only 3 cases confirmed by bone biopsy being reported in the literature (1–3). The case to be presented here is the fourth to be confirmed by histopathologic study and, in addition, showing complete regression without treatment. Osseous lesions occur in a small percentage of patients with sarcoidosis and are usually in the hands and feet. Case Report A 51-year-old white housewife was seen at the Marshfield Clinic (Marshfield, Wisc.) on Oct. 31, 1958, because of intermittent swelling of the neck for three years, along with occasional pains over the right side of her head and face. She had also noticed a “spot” on the left labium majus, with intermittent swelling and ulceration for two years. Physical examination revealed an almond-sized node in the right anterior cervical chain and a small right submandibular node, with no other adenopathy. The heart and lungs were normal, and the liver and spleen were not palpable. An annular lesion, 1 cm. in diameter, with an ulcera...