Carcinoma of the penis is more frequently seen in the treatment centers of Puerto Rico than of the continental United States. The incidence may be linked to racial, cultural, and socio-economic factors. Circumcision at birth has been associated with almost complete absence of this form of cancer; done later in life that procedure may diminish the incidence of the disease, but will not eliminate it. Carcinomas arise from the mucosal lining of the preputial sac, which is covered by modified skin. In contrast to carcinomas in other skin areas, these lesions are almost invariably of the epidermoid type and produce metastases in a significant percentage of cases. Since the penis is a very accessible organ, one is impressed by the fact that the five-year survival for penile cancer can be as low as 16 per cent (Furlong and Uhle, 12). The opinion prevailing in American centers is that the treatment of choice of the primary tumor is surgical ; a number of European centers, however, favor radiation therapy, reservi...