Peptic ulcer of the duodenum involving the postbulbar region presents important clinical and radiographic differences from the usual type of duodenal ulcer. It has been our experience that this type of ulceration is not a rarity, but occurs frequently enough to be given careful consideration in every patient undergoing gastrointestinal examination. The clinical findings in postbulbar duodenal ulcer do not differ significantly from those associated with the more commonplace ulcers of the bulb. It is important, then, for the radiologist to localize the site of ulceration accurately so that the clinician is better able to evaluate the future course and management. Bleeding occurs in 57 per cent of postbulbar ulcers, which is in striking contrast to the 19 per cent of bulbar ulcers and 23 per cent of gastric ulcers (1). This high incidence of bleeding, coupled with an increased frequency of intractability to treatment, makes the prognosis rather poor and demands special therapeutic considerations. The actual ...