The classical descriptions of Bucy and Capp (3) established the presently accepted roentgen criteria for the diagnosis of cavernous hemangioma of bone. In recent years, a rare and somewhat atypical form of cavernous hemangioma, aptly labeled “cystic angiomatosis” by Jacobs and Kimmelstiel (8), has been reported. As the name implies, there is widespread distribution of purely cystic lesions, which show none of the usual x-ray findings associated with hemangioma of vertebrae or flat bones. Nor are the lesions in the long bones entirely typical. A case of cystic angiomatosis, correctly diagnosed prior to definitive biopsy, will be presented in this article. So far as we know, it is the first to appear in the radiologic literature. A 15-year-old Negro boy was admitted to the Rochester Municipal Hospital on Oct. 28, 1955, with a fracture of the left femur sustained while playing football. Emergency roentgenography showed that the fracture had occurred in a cystic area and that several other cysts were present ...