Roentgenology offers a most satisfactory clinical approach to the finding of small polypoid defects in and beneath the gastric mucosa. These polypoid defects may be produced by a large variety of gastric diseases. The problems associated with their differentiation have been impressed upon us by our experience in recent months, and we have been led to review the entire subject of polypoid “filling defects” in the stomach. The literature is voluminous. The following represents a condensation of the most important aspects. Refinements in equipment and technic and a demand for early diagnosis of gastric cancer have produced and will continue to produce greater skill in the detection and diagnosis of these lesions. The phrase “polypoid disease” is purely descriptive and does not indicate any definite etiology. Rather it signifies a manifestation of gastric disease by the appearance of something polyp-like. Just as adenomatous polyps may be pedunculated or sessile, so this wide variety of polypoid lesions range...