This is a more or less preliminary report on those epitheliomas of the skin seen by me between June 1, 1921, and January 1, 1944. It is limited to epitheliomas having their origin in the skin; melanomas, benign and malignant, cancers arising in the mucous membranes, such as true lip cancers, and cancers metastasizing to the skin from other organs or tissues are not included. The biopsy reports show that the lesions were basal-cell, squamous-cell, and mixed basal- and squamous-cell cancers, cancers reported as basal- or squamous-cell but not possible to differentiate, papillary and transitional-cell cancers. The pathologists who made the reports in every instance placed the origin in skin structures. The number of lesions seen and treated before 1926 is relatively small, and most of the recurrences (15 of 25) are among those treated before that year. The dosage used at that time would today be considered inadequate. Roentgen rays were used in 1,205 of the cases treated, or 89.5 per cent; 4.5 per cent were ...