The Abdominal Fat Necrosis Sign

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 1971 English Publisher:Radiological Society of North America (RSNA)Journal:Radiology, volume 100, pages 567-571 (issn: 0033-8419, eissn: 1527-1315,

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Authors: J E, Berenson; H B, Spitz; B, Felson;

doi: 10.1148/100.3.567

pmid: 5567316

The Abdominal Fat Necrosis Sign

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Abstract

The fat necrosis sign is pathognomonic of acute pancreatitis. It can be recognized roentgenographically by faint mottled radiolucencies, probably representing normal fat interspersed with the water density of hydrolyzed or saponified fat. The sign is probably often associated with a precipitous drop in the serum calcium level as a result of mobilization of calcium into the necrotic areas in the form of calcium soaps. Although rare, this sign is diagnostic of acute pancreatitis with a high mortality rate.

Keywords

Adult, Fats, Male, Radiography, Necrosis, Pancreatitis, Humans, Calcium, Female, Peritoneum

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