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Endothelial Progenitor Cells

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 2005 English Publisher:Annual ReviewsJournal:Annual Review of Medicine, volume 56, pages 79-101 (issn: 0066-4219, eissn: 1545-326X,

Authors: Aarif Y. Khakoo; Toren Finkel;

doi: 10.1146/annurev.med.56.090203.104149

pmid: 15660503

Endothelial Progenitor Cells

- Summary
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Abstract

Endothelial progenitor cells are a circulating, bone marrow–derived cell population that appears to participate in both vasculogenesis and vascular homeostasis. Questions persist regarding their functional characteristics, as well as the precise panel of cell surface markers that uniquely define this newly described progenitor cell population. We review experimental results obtained from both animal studies and recent clinical trials that suggest this cell type may have tremendous therapeutic potential for a wide range of human diseases.

Related Organizations

National Institute of Health
Pakistan
National Institutes of Health
United States
Medical Research Council
United Kingdom
MRC Laboratory of Molecular Biology
United Kingdom

Keywords

Neovascularization, Pathologic, Stem Cells, Cell- and Tissue-Based Therapy, Myocardial Infarction, Myocardial Ischemia, Endothelial Cells, Neovascularization, Physiologic, Bone Marrow Cells, Disease Models, Animal, Ischemia, Antigens, Surface, Animals, Homeostasis, Humans, Cells, Cultured, Stem Cell Transplantation

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	302
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 1%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 1%