Reconciliation problems for duplication, loss and horizontal gene transfer

descriptionPublicationkeyboard_double_arrow_right Article , Conference object 01 Jan 2004Publisher:ACM PressJournal:Proceedings of the eighth annual international conference on Computational molecular biology - RECOMB '04

Authors: Pawel Górecki 0001;

doi: 10.1145/974614.974656

Reconciliation problems for duplication, loss and horizontal gene transfer

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Abstract

This paper presents a model of reconciling a species tree and a gene tree in an extended duplication-loss model. In the first part the definition of a model is introduced. In the second the horizontal transfer is defined and a new polynomial reconciliation algorithm is presented. We prove NP-completeness of the important problem related to the reconstruction of the species relationships with transfers from a given set of gene family trees. Some new problems are stated. We present a simple biological example.

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University of Warsaw
Poland

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