A programming system called LISP (for LISt Processor) has been developed for the IBM 704 computer by the Artificial Intelligence group at M.I.T. The system was designed to facilitate experiments with a proposed system called the Advice Taker, whereby a machine could be instructed to handle declarative as well as imperative sentences and could exhibit “common sense” in carrying out its instructions. The original proposal [1] for the Advice Taker was made in November 1958. The main requirement was a programming system for manipulating expressions representing formalized declarative and imperative sentences so that the Advice Taker system could make deductions. In the course of its development the LISP system went through several stages of simplification and eventually came to be based on a scheme for representing the partial recursive functions of a certain class of symbolic expressions. This representation is independent of the IBM 704 computer, or of any other electronic computer, and it now seems expedient to expound the system by starting with the class of expressions called S-expressions and the functions called S-functions.