Rate constants for oxygen exchange of methanol in sulfuric acid and perchloric acid solutions are reported, along with activity coefficients of methanol in sulfuric acid. Transition state activity coefficients (f≠*) for methanol exchange and tert-butanol exchange have been calculated. Values of f≠* for the latter behave very similarly to those for tert-butyl acetate hydrolysis, consistent with a carbonium ion-like transition state. Values for methanol exchange show considerably more salting-out, consistent with an oxonium ion-like transition state. A significant difference with the AAc2 hydrolyses of esters and amides is noted. For the latter the transition state is salted-out relative to its protonated precursor, whereas for methanol exchange, there is little difference between the activity coefficient of the protonated alcohol and the transition state, with the latter actually being somewhat salted-in. It is pointed out that the transition state activity coefficient approach can be rigorously applied even in the absence of protonation data.