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THE METABOLISM OF THE ERYTHROCYTE: XV. ADENYLATE KINASE OF THE ERYTHROCYTE

Name: THE METABOLISM OF THE ERYTHROCYTE: XV. ADENYLATE KINASE OF THE ERYTHROCYTE
Keywords: Erythrocytes, Adenylate Kinase, Phosphotransferases, Humans

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1958Publisher:Canadian Science PublishingJournal:Canadian Journal of Biochemistry and Physiology, volume 36, pages 1,057-1,064 (issn: 0576-5544,

Authors: Orville F. Denstedt; Shelby Kashket;

doi: 10.1139/o58-113 , 10.1139/y58-113

pmid: 13585210

THE METABOLISM OF THE ERYTHROCYTE: XV. ADENYLATE KINASE OF THE ERYTHROCYTE

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Abstract

Adenylate kinase has been found in the membrane and the cytoplasm of rabbit and human erythrocytes. ADP, when added to a suspension of washed erythrocytes, causes an increase in the rate of glucose utilization by the cells. The ADP evidently can enter the cell membrane where it is converted by the adenylate kinase to equimolar quantities of ATP and AMP. The ATP can pass either into the interior of the cell or into the external medium. Added ATP or AMP apparently cannot pass through the erythrocyte membrane. The role of adenylate kinase in these reactions, and its location within the erythrocyte membrane, are discussed.

Related Organizations

University of Montreal
Canada
McGill University
Canada

Keywords

Erythrocytes, Adenylate Kinase, Phosphotransferases, Humans

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	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	37
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	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average

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