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Occupational and Environmental Medicine
Article . 1971 . Peer-reviewed
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Paraquat in the rabbit

Authors: Cooley Butler; Jerome Kleinerman;

Paraquat in the rabbit

Abstract

Butler, C. II, and Kleinerman, J. (1971). Brit. J. industr. Med., 28, 67-71. Paraquat in the rabbit. Forty rabbits received paraquat intraperitoneally in total dosages of from 2 to 100 mg/kg and in one to five separate administrations. Nine animals which received 25 mg/kg or more died within four days of administration, and the remainder were killed at intervals of up to one month. The delayed pulmonary changes produced in man and other species by paraquat were not found in any animal, despite the fact that most animals were made ill by the chemical. Atrophy of the thymus and minimal renal tubular and focal peritoneal changes were present in animals found dead or killed soon after administration, but it was difficult to explain the cause of death.

Keywords

Animals

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    55
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
55
Average
Top 10%
Top 10%
bronze