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Multiple cranial nerve enlargement in Charcot-Marie-Tooth disease

Authors: William Huynh; Lynette Masters;

Multiple cranial nerve enlargement in Charcot-Marie-Tooth disease

Abstract

Hypertrophy of peripheral nerves are commonly reported in patients with demyelinating forms of Charcot-Marie-Tooth disease (CMT).1 Herein, an under-recognised association with hypertrophy of multiple cranial nerves in a patient with CMT is described. A 39-year-old otherwise healthy man presented with a 2-month history of tension-type headaches without other associated neurological symptoms. Examination showed normal visual acuity but mild blunting of the nasal disc margins bilaterally on funduscopy. No other cranial nerve abnormalities were elicited. In the lower limbs, there was prominent pes cavus deformity involving both feet (figure 1A) associated with subtle ankle dorsiflexion weakness and impaired distal proprioception. Power in the upper limbs was normal and deep tendon reflexes were globally depressed. Figure 1 (A) Lower limb of patient demonstrating classical pes cavus foot deformity; (B) MRI Brain: Coronal fat suppressed T2-weighted sequence showing enlargement of the maxillary nerves at the foramen rotundum; (B and C) Coronal …

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Keywords

Adult, Male, Charcot-Marie-Tooth Disease, Cranial Nerves, Brain, Humans, Neuroimaging, Magnetic Resonance Imaging

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
2
Average
Average
Average
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