
pmid: 33243855
Hypertrophy of peripheral nerves are commonly reported in patients with demyelinating forms of Charcot-Marie-Tooth disease (CMT).1 Herein, an under-recognised association with hypertrophy of multiple cranial nerves in a patient with CMT is described. A 39-year-old otherwise healthy man presented with a 2-month history of tension-type headaches without other associated neurological symptoms. Examination showed normal visual acuity but mild blunting of the nasal disc margins bilaterally on funduscopy. No other cranial nerve abnormalities were elicited. In the lower limbs, there was prominent pes cavus deformity involving both feet (figure 1A) associated with subtle ankle dorsiflexion weakness and impaired distal proprioception. Power in the upper limbs was normal and deep tendon reflexes were globally depressed. Figure 1 (A) Lower limb of patient demonstrating classical pes cavus foot deformity; (B) MRI Brain: Coronal fat suppressed T2-weighted sequence showing enlargement of the maxillary nerves at the foramen rotundum; (B and C) Coronal …
Adult, Male, Charcot-Marie-Tooth Disease, Cranial Nerves, Brain, Humans, Neuroimaging, Magnetic Resonance Imaging
Adult, Male, Charcot-Marie-Tooth Disease, Cranial Nerves, Brain, Humans, Neuroimaging, Magnetic Resonance Imaging
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