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Journal of Epidemiology & Community Health
Article . 2001 . Peer-reviewed
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A heuristic approach to the formulas for population attributable fraction

Authors: J A, Hanley;

A heuristic approach to the formulas for population attributable fraction

Abstract

BACKGROUND As the definitional formula for population attributable fraction is not usually directly usable in applications, separate estimation formulas are required. However, most epidemiology textbooks limit their coverage to Levin's formula, based on the (dichotomous) distribution of the exposure of interest in the population. Few present or explain Miettinen's formula, based on the distribution of the exposure in the cases; and even fewer present the corresponding formulas for situations with more than two levels of exposure. Thus, many health researchers and public health practitioners are unaware of, or are not confident in their use of, these formulas, particularly when they involve several exposure levels, or confounding factors. METHODS/RESULTS A heuristic approach, coupled with pictorial representations, is offered to help understand and interconnect the structures behind the Levin and Miettinen formulas. The pictorial representation shows how to deal correctly with several exposure levels, and why a commonly used approach is incorrect. Correct and incorrect approaches are also presented for situations where estimates must be aggregated over strata of a confounding factor.

Related Organizations
Keywords

Logistic Models, Models, Statistical, Population Surveillance, Humans, Demography

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
253
Top 1%
Top 1%
Average
bronze