Name: Distribution of immunoglobulin heavy chains in diseased synovia.
Keywords: immunology: Arthritis, alpha-Chain, analysis: Immunoglobulins, analysis: Immunoglobulins, alpha-Chain, Research Support, Non-U.S. Gov't, Heavy-Chain, Plasma Cells, Synovial Membrane, Cell Count, Research Support

descriptionPublicationkeyboard_double_arrow_right Article 01 Jul 1986 English Publisher:BMJJournal:Journal of Clinical Pathology, volume 39, pages 731-735 (issn: 0021-9746, eissn: 1472-4146,

Authors: Freemont, AJ; Rutley, C.;

doi: 10.1136/jcp.39.7.731

pmid: 3090108

pmc: PMC500033

Distribution of immunoglobulin heavy chains in diseased synovia.

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Abstract

Synovium from 142 patients with 12 different arthropathies was examined for the distribution of alpha, delta, gamma, and mu immunoglobulin heavy chains. A high proportion of plasma cells in the superficial subintima in all diseases reacted for alpha heavy chains. Only in rheumatoid disease did the synovium contain more than 10% of plasma cells reacting for mu heavy chains.

Related Organizations

University of Salford
United Kingdom

Keywords

immunology: Arthritis, alpha-Chain, analysis: Immunoglobulins, analysis: Immunoglobulins, alpha-Chain, Research Support, Non-U.S. Gov't, Heavy-Chain, Plasma Cells, Synovial Membrane, Cell Count, Research Support, Immunoglobulin alpha-Chains, immunology: Plasma Cells, Arthritis, Rheumatoid, immunology: Arthritis, Rheumatoid, immunology: Joint Diseases, Rheumatoid, immunology: Synovial Membrane, Humans, Joint Diseases, Non-U.S. Gov't, Immunoglobulin Heavy Chains, analysis: Immunoglobulins, Heavy-Chain

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