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pmid: 18515403
As a concept sentinel lymph node biopsy seems attractive in that it attempts to identify the first lymph node, rather than the nearest node, draining a particular anatomic area where a tumour has arisen. Pathological assessment can then indicate whether metastases are present and the procedure is either a strong prognostic indicator or possibly therapeutic in itself. These comments apply to any tumour type, but with melanoma the pathological procedure is more problematic and any benefits above prognosis and staging are not universally accepted. The procedure does give accurate staging without the extra morbidity of regional node dissection and many patients gain psychological support from the information gained.
Staining and Labeling, Reverse Transcriptase Polymerase Chain Reaction, Sentinel Lymph Node Biopsy, Lymphatic Metastasis, Patient Selection, Humans, Prognosis, Melanoma
Staining and Labeling, Reverse Transcriptase Polymerase Chain Reaction, Sentinel Lymph Node Biopsy, Lymphatic Metastasis, Patient Selection, Humans, Prognosis, Melanoma
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 23 | |
popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Average | |
influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 10% | |
impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Top 10% |