Functional heartburn: the stimulus, the pain, and the brain
Copyright policy )Functional heartburn: the stimulus, the pain, and the brain
Functional heartburn is a common disorder and appears to be composed of several distinct subgroups. Identifying the different subgroups based on clinical history only is not achievable at present. The mechanisms responsible for pain, clinical characteristics, and the optimal therapeutic approach remain poorly understood. Response to potent antireflux treatment is relatively limited. Current and future treatment strategies for functional heartburn patients who have failed standard dose proton pump inhibitors (PPIs) include increased PPI dose in some, as well as addition of pain modulators in others.
- University of Arizona United States
- University Health Care System United States
Male, Sensation, Proton Pump Inhibitors, Anti-Ulcer Agents, Esophagus, Heartburn, Gastroesophageal Reflux, Humans, Female, Serotonin Antagonists, Selective Serotonin Reuptake Inhibitors
Male, Sensation, Proton Pump Inhibitors, Anti-Ulcer Agents, Esophagus, Heartburn, Gastroesophageal Reflux, Humans, Female, Serotonin Antagonists, Selective Serotonin Reuptake Inhibitors
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