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▼Varenicline for smoking cessation

descriptionPublicationkeyboard_double_arrow_right Article 01 May 2008Publisher:BMJJournal:Drug and Therapeutics Bulletin, volume 46, pages 33-36 (issn: 0012-6543, eissn: 1755-5248,

doi: 10.1136/dtb.2008.04.0010

pmid: 18463392

▼Varenicline for smoking cessation

- Summary
- Subjects
- Metrics

Abstract

▼Varenicline (pronounced va-re-nik-leen) (Champix – Pfizer), a nicotinic receptor partial agonist, is the first medicine of this type licensed for smoking cessation in adults. Launched in the UK in December 2006, the drug accounted for 14% of all prescription items and 22% of total expenditure, for smoking cessation products dispensed in the community in 2007*.1–4 Marketing materials claim that it has a “unique dual action”, a “significantly higher quit rate” than bupropion, and a “favourable safety and tolerability profile”. Here we discuss the evidence for varenicline and consider its role in smoking cessation.

Keywords

Adult, Nicotinic Antagonists, Benzazepines, Drug Costs, Treatment Outcome, Meta-Analysis as Topic, Quinoxalines, Humans, Smoking Cessation, Varenicline, Randomized Controlled Trials as Topic

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	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average