
doi: 10.1136/bmj.g15
pmid: 24496166
#### Summary points Lower respiratory tract illnesses with wheeze are common, occurring in around a third of all preschool children (here defined as aged between 1 and 5 years). They are a major source of morbidity and healthcare costs, including time off work for carers, and are often difficult to treat. This review focuses on the two areas in which there have been recent developments. The first is the classification of these children by symptom pattern into “episodic viral” and “multiple trigger” wheezers.1 These phenotypes can change within an individual over time,2 but they are a useful guide to current treatment, and there are also physiological and pathological rationales for their use.3 4 The second area is the recent series of large randomised controlled trials of treatment, specifically related to the roles of intermittent montelukast and inhaled and oral corticosteroids. These trials have shown clearly that inhaled corticosteroids and prednisolone in particular have been misused and overused in the past, mandating a reappraisal of treatment algorithms. Video abstract #### Sources and selection criteria We performed a …
Adrenal Cortex Hormones, Child, Preschool, Prednisolone, Anti-Inflammatory Agents, Humans, Asthma, Respiratory Sounds
Adrenal Cortex Hormones, Child, Preschool, Prednisolone, Anti-Inflammatory Agents, Humans, Asthma, Respiratory Sounds
| selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 38 | |
| popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Top 10% | |
| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 10% | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Top 10% |
