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Article . 2013 . Peer-reviewed
Data sources: Crossref
BMJ
Article . 2011 . Peer-reviewed
Data sources: Crossref
BMJ
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Receiver operating characteristic curves

Authors: Philip Sedgwick;

Receiver operating characteristic curves

Abstract

Researchers evaluated the performance of a cognitive test called “test your memory” as a screening test for Alzheimer’s disease. The screening test is designed to use minimal operator time and to be suitable for non-specialist use. It is self administered under medical supervision. The test has a minimum score of zero and a maximum score of 50; lower scores indicate greater cognitive impairment.1 The study was based in hospital outpatient departments. Participants included 94 patients diagnosed as having Alzheimer’s disease. For each patient, three age matched healthy controls without Alzheimer’s disease (n=282) were recruited from accompanying relatives. All patients and controls completed the screening test. The optimal test score for discriminating between patients with Alzheimer’s disease and controls was investigated. Each score from 50 down to zero was taken successively as the cut-off point between a “negative” and “positive” screening test result; all scores less than or equal to the cut-off score were considered positive and others were considered negative. For each cut-off score the sensitivity and specificity of the screening test was calculated, and these values were used to derive a receiver operating characteristic curve (figure⇓). The area under the receiver operating characteristic curve was 0.95. Receiver operating characteristic curve for “test your memory” scores differentiating patients with Alzheimer’s disease (n=94) and age matched controls (n=282). Numbers on curve refer to a range of selected cut-off scores between “negative” and “positive” results Which of the following statements, if any, are true?

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
35
Top 10%
Top 10%
Top 10%
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