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Meta-analyses: how to read a funnel plot

Authors: P. Sedgwick;

Meta-analyses: how to read a funnel plot

Abstract

Researchers undertook a meta-analysis to evaluate the relative short term safety of carotid endarterectomy compared with carotid artery stenting.1 Randomised controlled trials were included if they compared carotid endarterectomy with carotid artery stenting in patients with carotid artery stenosis (with or without symptoms). In total, 10 trials were identified that reported short term outcomes. The primary endpoint was mortality or stroke within 30 days of the procedure. The total overall periprocedural risk of mortality or stroke was lower for carotid endarterectomy than for carotid artery stenting (odds ratio 0.67, 95% confidence interval 0.47 to 0.95; P=0.025). A funnel plot was presented (figure⇓). Egger’s test gave a P value equal to 0.932. Funnel plot for the meta-analysis of the short term safety (periprocedural mortality or stroke) of carotid endarterectomy compared with carotid artery stenting Which of the following statements, if any, are true? Statements a and b are true, whereas c is false. The meta-analysis investigated the relative short term safety of carotid endarterectomy compared with carotid artery stenting. Ten trials were identified …

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
118
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Top 10%
Top 10%
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