A more balanced perspective The BBC’s Panorama programme The Mind Reader: Unlocking My Voice broadcast on 13 November 2012 provided important insights into the devastating experience of patients who live in vegetative or minimally conscious states and the families who support them. It also provided useful information on the use of functional magnetic resonance imaging (fMRI) to explore evidence of localised brain activity that might indicate underlying awareness. However, the programme failed to distinguish clearly between the two states and gave the impression that 20% of patients in a vegetative state show cognitive responses on fMRI. This claim needs to be clarified and put into perspective. There are important differences between the two states. Patients in a vegetative state have no discernible awareness of self and no cognitive interaction with their environment. Patients in a minimally conscious state show evidence of interaction through localising or discriminating behaviours, although such interactions occur inconsistently. It is clinically important to make this distinction, for prognostic reasons and because some evidence suggests that patients in a minimally conscious state experience symptoms (such as pain) in a manner indistinguishable from non-brain injured patients.1 2 The programme presented two patients said to be in a “vegetative state” who showed evidence of cognitive interaction on assessment using fMRI in Ontario, Canada. The clinical methods used for the original diagnosis …