
doi: 10.1136/bmj.e5980
Researchers investigated the risk of colorectal cancer after screening with flexible sigmoidoscopy. A randomised controlled study was undertaken in Norway with a population based sample. The intervention consisted of once only flexible sigmoidoscopy screening with or without a single round of faecal occult blood testing. The control treatment was no screening. The main outcome measures included length of time from randomisation until death from colorectal cancer.1 After a median of six years of follow-up, the hazard ratio for mortality from colorectal cancer, comparing intervention with control, was 0.73 (95% confidence interval 0.47 to 1.13). The researchers concluded that mortality from colorectal cancer was not significantly reduced in the screening group but that it seemed to be lower among participants who attended screening.
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