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Pharmacogenetics in the rheumatic diseases

Name: Pharmacogenetics in the rheumatic diseases
Creator: Bruce N. Cronstein
Keywords: Treatment Outcome, Pharmacogenetics, Antirheumatic Agents, Rheumatic Diseases, 0103 physical sciences, Humans, 01 natural sciences, 3. Good health

descriptionPublicationkeyboard_double_arrow_right Article 01 Nov 2004 English Publisher:Elsevier BVJournal:Annals of the Rheumatic Diseases, volume 63, pages ii25-ii27 (issn: 0003-4967,

Authors: Bruce N. Cronstein;

doi: 10.1136/ard.2004.028217

pmid: 15479867 , 17121484

pmc: PMC1766779

Pharmacogenetics in the rheumatic diseases

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Abstract

Designing a therapeutic plan that involves the least risk of toxicity and the greatest chance of success is the goal of the modern physician. To better achieve this goal an understanding of the genetic basis for drug efficacy and toxicity is essential. Here we review the available information on the pharmacogenetics of drugs commonly used to treat rheumatic diseases in the hope that the application of this information to the patient will contribute to more effective and safer therapies for rheumatoid arthritis, systemic lupus erythematosus, and other inflammatory diseases.

Related Organizations

University of Chicago
United States
New York University
United States

Keywords

Treatment Outcome, Pharmacogenetics, Antirheumatic Agents, Rheumatic Diseases, Humans

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	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	12
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	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average