
Sixty children, aged between 2 and 10 years, had boutonneuse fever during the summer months of 1979 and 1980. They presented with fever and a generalised maculopapular rash. The tàche noire could be seen at the site of the tick bite in 38 (63%) of them. The antibody response, assayed nonspecifically, by the Weil-Felix reaction was positive in 52. A singe titre of more than 1:80 or a 4-fold increase between two paired specimens separated by a 7-day interval was considered diagnostic. Maximum titres were reached at the end of the second week of convalescence in 81% of patients. Treatment with oral oxytetracycline was effective in all cases.
Child, Preschool, Antibody Formation, Humans, Rickettsiaceae Infections, Boutonneuse Fever, Child, Skin
Child, Preschool, Antibody Formation, Humans, Rickettsiaceae Infections, Boutonneuse Fever, Child, Skin
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