Name: The mitochondrial genome. The nucleoid
Creator: Alexander A. Kolesnikov
Keywords: Mitochondrial Proteins, 0301 basic medicine, 0303 health sciences, 03 medical and health sciences, Genome, Mitochondrial, Animals, Humans, DNA, Mitochondrial, Mitochondria

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 2016 English Publisher:Pleiades Publishing LtdJournal:Biochemistry (Moscow), volume 81, pages 1,057-1,065 (issn: 0006-2979, eissn: 1608-3040,

Authors: Alexander A. Kolesnikov;

doi: 10.1134/s0006297916100047

pmid: 27908231

The mitochondrial genome. The nucleoid

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Abstract

Mitochondrial DNA (mtDNA) in cells is organized in nucleoids containing DNA and various proteins. This review discusses questions of organization and structural dynamics of nucleoids as well as their protein components. The structures of mt-nucleoid from different organisms are compared. The currently accepted model of nucleoid organization is described and questions needing answers for better understanding of the fine mechanisms of the mitochondrial genetic apparatus functioning are discussed.

Related Organizations

Lomonosov Moscow State University
Russian Federation

Keywords

Mitochondrial Proteins, Genome, Mitochondrial, Animals, Humans, DNA, Mitochondrial, Mitochondria

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