
pmid: 21568863
Translation initiation factor 2 (IF2) is one of key components of the translation initiation system in living cells. In bacteria IF2 is a multidomain monomeric protein, while in eukaryotic and archaean cells e/aIF2 is heterotrimer (αβγ). Data, including our own, on eukaryotic type translation initiation factor 2 (e/aIF2) structure and functioning are presented. There are also new data on initiation factors eIF5 and eIF2B that directly interact with eIF2 and control its participation in nucleotide exchange.
Structure-Activity Relationship, RNA, Transfer, Met, Protein Biosynthesis, Eukaryotic Initiation Factor-2, Animals, RNA, Messenger, Ribosome Subunits, Small
Structure-Activity Relationship, RNA, Transfer, Met, Protein Biosynthesis, Eukaryotic Initiation Factor-2, Animals, RNA, Messenger, Ribosome Subunits, Small
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