c-di-GMP Inhibits Early Sporulation in Clostridioides difficile
Copyright policy )c-di-GMP Inhibits Early Sporulation in Clostridioides difficile
Many bacterial organisms utilize the small signaling molecule cyclic diguanylate (c-di-GMP) to regulate important physiological processes, including motility, toxin production, biofilm formation, and colonization. c-di-GMP inhibits motility and toxin production and promotes biofilm formation and colonization in the anaerobic, gastrointestinal pathogen Clostridioides difficile . However, the impact of c-di-GMP on C. difficile spore formation, a critical step in this pathogen’s life cycle, is unknown.
- Emory University United States
- UNIVERSITY OF NORTH CAROLINA CHAPEL HILL
- Emory University School of Medicine United States
- Emory University School of Medicine
- Emory University School of Medicine United States
Spores, Bacterial, sporulation, Clostridioides difficile, Bacterial Toxins, Clostridium difficile, c-di-GMP, Gene Expression Regulation, Bacterial, spore, Microbiology, QR1-502, Bacterial Proteins, cyclic diguanylate, Cyclic GMP, Research Article
Spores, Bacterial, sporulation, Clostridioides difficile, Bacterial Toxins, Clostridium difficile, c-di-GMP, Gene Expression Regulation, Bacterial, spore, Microbiology, QR1-502, Bacterial Proteins, cyclic diguanylate, Cyclic GMP, Research Article
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