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Molecular Mechanisms of Poxvirus Evolution

Authors: Greg Brennan; Ana M. M. Stoian; Huibin Yu; M. Julhasur Rahman; Shefali Banerjee; Jeannine N. Stroup; Chorong Park; +2 Authors

Molecular Mechanisms of Poxvirus Evolution

Abstract

Poxviruses are often thought to evolve relatively slowly because they are double-stranded DNA pathogens with proofreading polymerases. However, poxviruses have highly adaptable genomes and can undergo relatively rapid genotypic and phenotypic change, as illustrated by the recent increase in human-to-human transmission of monkeypox virus.

Country
United States
Keywords

Gene duplication, 3105 Genetics (for-2020), Host Specificity (mesh), 0605 Microbiology (for), Gene Duplication, 2.1 Biological and endogenous factors, 3101 Biochemistry and cell biology (for-2020), Humans (mesh), 3107 Microbiology (for-2020), poxviruses, Horizontal gene transfer, Poxviruses, Biological Sciences, Medical microbiology, QR1-502, Molecular (mesh), Infectious Diseases, horizontal gene transfer, Biotechnology, 570, DNA recombination, Evolution, 610, Biotechnology (rcdc), Microbiology, Emerging Infectious Diseases (rcdc), Gene Duplication (mesh), Host Specificity, Rare Diseases (rcdc), Evolution, Molecular, Rare Diseases, Biodefense, evolution, Genetics, Humans, Biodefense (rcdc), Small Pox, 31 Biological Sciences (for-2020), Genetics (rcdc), Poxviridae, gene duplication, Molecular, Small Pox (rcdc), 2.1 Biological and endogenous factors (hrcs-rac), Poxviridae (mesh), 3207 Medical microbiology (for-2020), Emerging Infectious Diseases, Infectious Diseases (rcdc), Biochemistry and cell biology, Minireview

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    popularity
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    influence
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
62
Top 1%
Top 10%
Top 1%
Green
gold