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In contrast to chick embryo fibroblast protein synthesis, the bulk of the protein synthesis directed by Semliki Forest virus is carried out on membranes. Under conditions where more than 95% of cell protein synthesis was inhibited, viral polysomes could be demonstrated. Viral protein appeared to be produced on polysomes associated with nascent ribonucleic acid strands still attached to the base-paired, double-stranded replicative form of the virus. Very rapid incorporation of virus protein into 140 S virus core particles was also demonstrated.
Viral Proteins, Ribonucleases, Protein Biosynthesis, Dactinomycin, Animals, RNA, RNA, Viral, Chick Embryo, Interferons, Fibroblasts, Virus Replication, Semliki forest virus
Viral Proteins, Ribonucleases, Protein Biosynthesis, Dactinomycin, Animals, RNA, RNA, Viral, Chick Embryo, Interferons, Fibroblasts, Virus Replication, Semliki forest virus
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 53 | |
popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Average | |
influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 10% | |
impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Top 10% |