Evaluation of the hemagglutination treponemal test for syphilis
Copyright policy )Evaluation of the hemagglutination treponemal test for syphilis
The sensitivity and specificity of the hemagglutination treponemal test for syphilis (HATTS) was compared with the fluorescent treponemal antibody-absorption test (FTA-ABS) with 491 sera. Medical histories were obtained for 153 patients with seroreactivity in either treponemal test. Overall correlation with patient history was 96.7% for the FTA-ABS and 93.9% for the HATTS. False-negative HATTS occurred in primary, late-latent (greater than 2 years), and treated syphilis. The reproducibility of the HATTS and FTA-ABS is equivalent. HATTS is an acceptable treponemal confirmatory test for syphilis, but the FTA-ABS should be used to resolve diagnostic discrepancies.
Fluorescent Antibody Technique, Hemagglutination Tests, Antibodies, Bacterial, Syphilis Serodiagnosis, Evaluation Studies as Topic, Humans, False Positive Reactions, Reagent Kits, Diagnostic, Treponema pallidum, False Negative Reactions
Fluorescent Antibody Technique, Hemagglutination Tests, Antibodies, Bacterial, Syphilis Serodiagnosis, Evaluation Studies as Topic, Humans, False Positive Reactions, Reagent Kits, Diagnostic, Treponema pallidum, False Negative Reactions
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