descriptionPublicationkeyboard_double_arrow_right Article 01 Nov 1989 English Publisher:American Society for MicrobiologyJournal:Journal of Bacteriology, volume 171, pages 6,391-6,393 (issn: 0021-9193, eissn: 1098-5530,

Authors: Joaquin Soler; Dolores de Arriaga; Javier Rúa; Félix Busto;

doi: 10.1128/jb.171.11.6391-6393.1989

pmid: 2808307

pmc: PMC210520

Effect of glucose on isocitrate lyase in Phycomyces blakesleeanus

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Abstract

Repression of the synthesis of isocitrate lyase by glucose and/or induction of the synthesis of isocitrate lyase by acetate in Phycomyces blakesleeanus were demonstrated. Both glycerol and ethanol failed to induce isocitrate lyase activity. Furthermore, glucose appeared to cause an in vivo catabolite inactivation of the derepressed enzyme. Isocitrate lyase was inactivated both reversibly and irreversibly by glucose.

Related Organizations

University of Leon
Spain

Keywords

Ethanol, Oxo-Acid-Lyases, Acetates, Isocitrate Lyase, Kinetics, Glucose, Phycomyces, Enzyme Induction, Mucorales, Cycloheximide, Enzyme Repression

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