
The addition of mannitol to cultures of Salmonella typhimurium mutants missing mannitol-1-phosphate dehydrogenase causes stasis or lysis. Mannitol-1-phosphate accumulates intracellularly to concentrations of 20 m m . The incorporation of acetate into lipid is inhibited before cell wall, protein, or nucleic acid synthesis.
Genetics, Microbial, Salmonella typhimurium, Carbon Isotopes, Time Factors, Chromatography, Paper, Phenylalanine, Pimelic Acids, Stereoisomerism, Microbial Sensitivity Tests, Acetates, Tritium, Lipids, Alcohol Oxidoreductases, Bacteriolysis, Bacterial Proteins, Cell Wall, Nucleic Acids, Mutation, Mannitol, Uracil
Genetics, Microbial, Salmonella typhimurium, Carbon Isotopes, Time Factors, Chromatography, Paper, Phenylalanine, Pimelic Acids, Stereoisomerism, Microbial Sensitivity Tests, Acetates, Tritium, Lipids, Alcohol Oxidoreductases, Bacteriolysis, Bacterial Proteins, Cell Wall, Nucleic Acids, Mutation, Mannitol, Uracil
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