
Cefamandole is a new cephalosporin antibiotic that was tested in vitro against 540 clinical isolates of gram-positive cocci and gram-negative bacilli. A concentration of 0.39 μg/ml inhibited 95% of the isolates of Staphylococcus aureus . A concentration of 6.25 μg/ml inhibited over 90% of the isolates of Proteus mirabilis and Escherichia coli , 69% of the isolates of Klebsiella pneumoniae , and 31% of the isolates of indole-positive Proteus spp. and Enterobacter spp. It was active against most cephalothin-resistant isolates of E. coli but not of K. pneumoniae .
Cephalexin, Staphylococcus aureus, Bacteria, Streptococcus, Bacterial Infections, Proteus, Cephalosporins, Cefoxitin, Klebsiella pneumoniae, Species Specificity, Cephalothin, Escherichia coli, Serratia marcescens
Cephalexin, Staphylococcus aureus, Bacteria, Streptococcus, Bacterial Infections, Proteus, Cephalosporins, Cefoxitin, Klebsiella pneumoniae, Species Specificity, Cephalothin, Escherichia coli, Serratia marcescens
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