Binding of Aminoglycosides to Feces

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 1974 English Publisher:American Society for MicrobiologyJournal:Antimicrobial Agents and Chemotherapy, volume 6, pages 415-417 (issn: 0066-4804, eissn: 1098-6596,

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Authors: G H, Wagman; J V, Bailey; M J, Weinstein;

doi: 10.1128/aac.6.4.415

pmid: 4157336

pmc: PMC444662

Binding of Aminoglycosides to Feces

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Abstract

Gentamicin and several other basic antibiotics were examined for their ability to adsorb to dog feces. It was found that 44 to 90% of all antibiotics studied were adsorbed to feces depending on the ratio of antibiotic to fecal material. Attempts to extract these antibiotics by acid treatment after adsorption onto feces were only partially successful since large portions of the bound materials were not removed.

Related Organizations

Schering-Plough
United States

Keywords

Feces, Dogs, Animals, Adsorption, Gentamicins, Anti-Bacterial Agents

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