Fungicidal activity of cecropin A

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 1997 English Publisher:American Society for MicrobiologyJournal:Antimicrobial Agents and Chemotherapy, volume 41, pages 481-483 (issn: 0066-4804, eissn: 1098-6596,

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Authors: A J, DeLucca; J M, Bland; T J, Jacks; C, Grimm; T E, Cleveland; T J, Walsh;

doi: 10.1128/aac.41.2.481

pmid: 9021214

pmc: PMC163736

Fungicidal activity of cecropin A

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Abstract

Cecropin A (CA) fungicidal properties were explored. Nongerminated and germinated Aspergillus spp. and Fusarium spp. conidia were treated with CA. CA achieved complete lethality at < or = 25 microM (99 micrograms/ml) for germinating, but not nongerminating, conidia of Aspergillus spp. CA achieved total lethality for nongerminated and germinating conidia of Fusarium spp at 1.5 microM (6 micrograms/ml). MIC and minimal lethal concentration assays in buffered RPMI medium gave similar results.

Related Organizations

United States Department of Agriculture
United States
Southern Regional Research Center
United States
Agricultural Research Service
United States

Keywords

Antifungal Agents, Aspergillus, Cholesterol, Fusarium, Ergosterol, Microbial Sensitivity Tests, Spores, Fungal, Peptides, Antimicrobial Cationic Peptides

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