Effect of food on absorption of lomefloxacin
Copyright policy )Effect of food on absorption of lomefloxacin
Twelve subjects participated in an open-label, single-dose, balanced three-way crossover study in which the absorptions of lomefloxacin were compared following (i) an overnight fast, (ii) a carbohydrate meal, and (iii) a high-fat meal. The time to peak concentration of lomefloxacin was delayed, but peak concentration in plasma and amount of drug absorbed were unchanged following both meals.
- University of Queensland Australia
- University of Queensland Australia
- Royal Brisbane and Women's Hospital Australia
- University of Queensland Australia
Pharmacology, Adult, Male, 4-Quinolones, Time Factors, Quinolones, Absorption, Infectious Diseases, Anti-Infective Agents, Food, 2736 Pharmacology (medical), Humans, Pharmacology (medical), Female, Chromatography, High Pressure Liquid, Fluoroquinolones
Pharmacology, Adult, Male, 4-Quinolones, Time Factors, Quinolones, Absorption, Infectious Diseases, Anti-Infective Agents, Food, 2736 Pharmacology (medical), Humans, Pharmacology (medical), Female, Chromatography, High Pressure Liquid, Fluoroquinolones
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