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Antimicrobial Agents and Chemotherapy
Article . 1986 . Peer-reviewed
License: ASM Journals Non-Commercial TDM
Data sources: Crossref
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Oral rimantadine hydrochloride therapy of influenza A virus H3N2 subtype infection in adults

Authors: F G, Hayden; A S, Monto;

Oral rimantadine hydrochloride therapy of influenza A virus H3N2 subtype infection in adults

Abstract

In a randomized, double-blind trial involving patients with uncomplicated influenza A H3N2 subtype virus infection, rimantadine treatment (200 mg/day for 5 days) was associated with significant reductions in nasal secretion viral titers (days 2 through 4), maximal temperature (days 2 and 3), time until defervescence (mean, 37 h shorter), and systemic symptoms compared with placebo treatment.

Related Organizations
Keywords

Adult, Male, Clinical Trials as Topic, Influenza A Virus, H3N2 Subtype, Administration, Oral, Adamantane, Body Temperature, Nasal Mucosa, Random Allocation, Rimantadine, Double-Blind Method, Influenza A virus, Influenza, Human, Humans, Female

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    81
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 1%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
Powered by OpenAIRE graph
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
81
Top 10%
Top 1%
Top 10%
bronze