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Antimicrobial Agents and Chemotherapy
Article
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Antimicrobial Agents and Chemotherapy
Article . 1985 . Peer-reviewed
License: ASM Journals Non-Commercial TDM
Data sources: Crossref
Antimicrobial Agents and Chemotherapy
Article . 1986
Data sources: Europe PubMed Central
Antimicrobial Agents and Chemotherapy
Article
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Antibacterial activities of antineoplastic agents

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 1985Publisher:American Society for MicrobiologyJournal:Antimicrobial Agents and Chemotherapy, volume 28, pages 437-439 (issn: 0066-4804, eissn: 1098-6596, Copyright policy )
Authors: James H. Jorgensen; David J. Drutz; C A Bodet;

doi: 10.1128/aac.28.3.437

pmid: 2416271

pmc: PMC180269

Antibacterial activities of antineoplastic agents

Abstract

Fourteen antineoplastic agents were examined for in vitro antibacterial activity against 101 aerobic and anaerobic bacterial isolates representing indigenous human microflora and selected opportunistic pathogens. Only 5-fluorouracil, mitomycin, and etoposide demonstrated inhibitory effects at achievable plasma concentrations, while the remaining drugs lacked appreciable antibacterial activities.

Related Organizations
Keywords

Bacteria, Mitomycin, Antineoplastic Agents, Microbial Sensitivity Tests, Mitomycins, Bleomycin, Methotrexate, Doxorubicin, Fluorouracil, Etoposide

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 75
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
75
Top 10%
Top 10%
Top 10%
bronze
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