N-formimidoyl thienamycin (MK0787): in vitro study

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1981 English Publisher:American Society for MicrobiologyJournal:Antimicrobial Agents and Chemotherapy, volume 19, pages 201-204 (issn: 0066-4804, eissn: 1098-6596,

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Authors: S, Shadomy; R S, May;

doi: 10.1128/aac.19.1.201

pmid: 6941741

pmc: PMC181385

N-formimidoyl thienamycin (MK0787): in vitro study

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Abstract

N-Formimidoyl thienamycin (MK0787) was compared in vitro with three other beta-lactam and two aminoglycoside antibiotics. It was second in activity only to cefotaxime against members of the Enterobacteriaceae and to amikacin against Pseudomonas species. It was the most active antibiotic against Staphylococcus aureus. Resistance (minimal inhibitory concentration, greater than 128 microgram/ml) to N-formimidoyl thienamycin was not observed.

Related Organizations

Virginia Commonwealth University
United States

Keywords

Imipenem, Bacteria, Enterobacteriaceae, Lactams, Pseudomonas, Microbial Sensitivity Tests, Anti-Bacterial Agents

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