Chemotherapy of Babesia microti infections in Mongolian Jirds

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 1980 English Publisher:American Society for MicrobiologyJournal:Antimicrobial Agents and Chemotherapy, volume 18, pages 289-291 (issn: 0066-4804, eissn: 1098-6596,

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Authors: T K, Ruebush; P G, Contacos; E A, Steck;

doi: 10.1128/aac.18.2.289

pmid: 7447406

pmc: PMC283985

Chemotherapy of Babesia microti infections in Mongolian Jirds

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Abstract

For identifying drugs which might be effective in the treatment of human Babesia microti infections, 20 selected antiprotozoal agents or combinations of agents were tested for activity against B. microti in Mongolian jirds (meriones unguiculatus). 4-Methyl-primaquine and aromatic diamidines, including diminazene and pentamidine, were the most effective compounds tested.

Keywords

Male, Structure-Activity Relationship, Babesiosis, Antiprotozoal Agents, Animals, Gerbillinae

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