Antiviral and interferon-inducing properties of interferon inducers administered with prostaglandins

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 1980 English Publisher:American Society for MicrobiologyJournal:Antimicrobial Agents and Chemotherapy, volume 17, pages 455-460 (issn: 0066-4804, eissn: 1098-6596,

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Authors: D A, Stringfellow;

doi: 10.1128/aac.17.3.455

pmid: 6158913

pmc: PMC283808

Antiviral and interferon-inducing properties of interferon inducers administered with prostaglandins

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Abstract

Prostaglandins enhanced the interferon response and therapeutic activity of interferon inducers in Friend leukemia virus-infected mice. A similar enhancement in interfron responsiveness but not antiviral activity was observed in mice infected with rapidly acute viruses.

Keywords

Male, Interferon Inducers, Leukemia, Experimental, Prostaglandins E, Prostaglandins F, Drug Synergism, Tilorone, Friend murine leukemia virus, Mice, Poly I-C, Pyrimidines, Virus Diseases, Animals, Female, Interferons

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